There are some fundamental obstacles that STSCI’s MAST and NIH’s research networks both face. First is the scale of the data. At STSCI, the big data is petabytes of imagery and sensor data from NASA’s space telescopes and other astronomy missions, as well as data from ground-based astronomy. At NIH, the “big data” that is most often in play is genomic data—a single individual’s genome is three billion base pairs of data. Hundreds of thousands of genomes are being analyzed at a time by researchers hoping to find patterns in genes related to cancer or other illnesses.